The next speaker, Venkatesh Sadananda Rao from the Department of Visceral, Thoracic and vascular Surgery, Dresden University of Technology, elucidated the role of extravesicular tissue inhibitor of matrix metalloproteinase-1 (TIMP1) in colorectal cancer (CRC) and colorectal liver metastasis samples during invasion and metastasis. This evidence concerns the gene TIMP1 and colorectal carcinoma.