Clinical monitoring of cachexia requires regular assessments of several parameters, including body weight loss and composition, inflammation [such as increased interleukin-6 (IL-6) or C-reactive protein], metabolic disturbances (such as anemia or low serum albumin), immunosuppression (such as low absolute lymphocyte number), decreased muscle strength and physical performance, fatigue, and anorexia[5,32,35]. The gene discussed is IL6; the disease is Anorexia.