EDN1 and stroke disorder: According to the results, we found that the number of BrdU/Olig2 positive cells in ET-1 group was not evidently different from that in Sham group at 35 days after stroke, but ET-1 + STIM group significantly promoted the proliferation of Olig2 labeled oligodendrocytes (p < 0.001 vs ET-1, Figure 7B).