EDN1 and stroke disorder: Next, we noted an obvious elevation in BrdU+/DCX+ cells on the ipsilateral side in the ET-1 group compared to the Sham group, with the increase in contralateral BrdU+/DCX+ cells similar to that on the ipsilateral side (p < 0.05, p < 0.05, Figure 5D), suggesting that only a small fraction of stroke-derived NSCs developed into neuroblasts.