PLOD1 and polycystic ovary syndrome: Previous studies indicated that inappropriately high LH levels might affect oocytematuration and fertilization rates, and impaired embryo quality, consequently resulting inhigher rates of impaired pregnancy and miscarriage in women with PCOS (Balen et al., 1993a,b; Homburg etal., 1993; Shoham etal., 1993; Jabara andCoutifaris, 2003; Urman etal., 2004; Santos et al.,2010).