KIT and constipation disorder: Ning’s (35) research involves stimulating a specific acupoint in the constipation model mice through acupuncture, and it has been found that acupuncture can regulate the slow wave frequency and amplitude of the mouse colon, increase the number of interstitial cells of Cajal (ICC) in the colon, promote the upregulation of c-kit protein expression, and alleviate constipation symptoms.