SACK1A and esophageal cancer: This is consistent with previous studies on esophageal cancer, where silencing TUG1 impeded the proliferation and invasion of cancer cells by affecting miR-1294.20 Additionally, knockdown of FAM83A-AS1,21 ELFN1-AS1,22 and SNHG723 reportedly has the potential to inhibit esophageal cancer cell activity.