When we compared females and males with myocarditis, we found males with myocarditis (blue) had significantly enriched clusters (i.e., auto-annotated grouped gene sets) for the following gene pathways compared to females: regulation mediated (immune) response, viral life cycle, presentation MHC antigen, Fc-receptor complement cascade, nucleoside activity anhydrides, abnormal thrombocyte morphology, and activity of serine peptidases (Fig. 2c). This evidence concerns the gene HLA-C and myocarditis.