In one case series of 64 cases of M-AML, and 57 cases of AML without monocytic differentiation (NM-AML), LILRB1 and/or LILRB4 positivity distinguished monocytes/monoblasts of M-AML from myeloblasts from NM-AML with 100% sensitivity and specificity [17]. The gene discussed is LILRB1; the disease is acute myeloid leukemia.