PAK6 and hepatocellular carcinoma: Although either high miR-3191 or low PAK6 in HCC predicts a poor prognosis (Fig. 5J), HCC patients with both elevated miR-3191 level and reduced PAK6 expression displayed even worse prognosis (Fig. 5K), indicating a better prognostic value of combining the two parameters in comparison with miR-3191 or PAK6 alone.