Our current investigation replicated the findings of the initial PGC-PTSD epigenome-wide meta-analysis, reporting lower AHRR methylation in those with PTSD, and identified 9 new (11 total) loci associated with PTSD, as well as 14 CpGs associated in analyses of specific strata (military vs civilian cohort, sex, and ancestry). Here, AHRR is linked to post-traumatic stress disorder.