By analyzing data from a previously reported AD proteomics study [53], we discovered that CD2AP levels were positively correlated with C1qa, C1qb, and C1qc levels in nearly all groups (control, asymptomatic AD patients, AD patients, and combined), except with C1qa and C1qb in AD groups (Supplemental Fig. 11A-C). This evidence concerns the gene C1QC and Alzheimer disease.