Moreover, MV (β = -5.22, P-value < 0.001), vasopressors (β = -2.26, P-value < 0.001), insulin (β = -0.48, P-value = 0.004), RFA (β = -4.38, P-value < 0.001), sepsis (β = -2.63, P-value < 0.001) and AKI (β = -1.78, P-value < 0.001) were associated with poorer GCS, while thrombolysis (β = 1.18, P-value < 0.001) was associated with better GCS. This evidence concerns the gene INS and acute kidney injury.