Neutrophilic diseases predominantly expressed genes related to neutrophils with expressions of PECAM1 (receptor involved in neutrophil transmigration), IL-1B and IL-6 (regulator of neutrophil trafficking), CR1, TNFAIP6, MME (neutrophil receptors and molecules), RUNX1, SPP1 (neutrophil attracting chemokine), neutrophil-secreted chemokines (CCL3, CCL4). The gene discussed is MME; the disease is functional neutrophil defect.