CYP2J2 and neoplasm: However, the in vivo and in vitro results showed that neither regulation of CYP2J2 nor treatment of EpOME could significantly impact the lipid accumulation and associated genes expression in tumor tissue or adipocytes, (Fig. S3I–T), indicating that lipid accumulation plays a limited role in the tumor-promoting effect of CYP2J2/EpOME on TNBC.