We then examined the mRNA and protein expression of the two genes in the MMTV-PyMT tumor tissues and the control mammary tissues and found that both Cxcl9 and Cxcl10 were significantly upregulated in the tumor tissues, and significantly decreased by inhibition of CYP monooxygenases (Fig. 5D and Supplementary Fig. S4D and S4E). The gene discussed is CXCL10; the disease is neoplasm.