In fact, the marker genes of the GABRA receptor families and cystine transporter xCT (SLA7A11 and CD44v), as well as antioxidation-controlled factors, such as JDP2, NRF2, and CDKN1A (p21Cip1), were significantly mutated in brain tumors, e.g., glioblastoma, glioma, and neuroblastoma (Fig. S4A, B). The gene discussed is JDP2; the disease is central nervous system cancer.