In the EML4-ALK-negative NSCLC cell line, A549, AKT inhibition in the presence or absence of LOR did not affect their cell viability with IC50 values of 150.9 and 135.87 μM, respectively, neither induced cell death (Supplementary Fig. S14A–C). The gene discussed is AKT1; the disease is non-small cell lung carcinoma.