EGF and neoplasm: EGF treatment significantly increased the size of tumor spheroids in both cell lines when BAY-805 was absent, compared to vehicle treatment without BAY-805 (Fig. 6B, C: HCT-15 + EGF without BAY-805 vs. HCT-15 + vehicle without BAY-805; Fig. 6D, E: HT-29 + EGF without BAY-805 vs. HT-29 + vehicle without BAY-805).