Slc25a21AAV9 mice exhibited decreased cell apoptosis in the kidneys following cisplatin injection compared to NCAAV9 AKI mice, as shown by the lower TUNEL-positive cells (Fig. 2E) and expression of BAX and Cleaved-Caspase 3 (Fig. 2F, Fig. S2F). This evidence concerns the gene BAX and acute kidney injury.