Both levels of SCr and BUN were strongly negatively correlated with the expression of Slc25a21 in cisplatin-induced AKI mouse kidneys following AAV application (Fig. S2E), with correlation coefficients of r = –0.92 (P = 0.0004) and r = –0.76 (P = 0.0176), respectively. Here, SLC25A21 is linked to acute kidney injury.