Among them, three genes (SERPINE1, DGKI, and MEF2B) closely related to the prognosis of patients with CRC were selected (Supplementary Fig. S20B, C) and the effects of LINC02257 and miR-1273g-3p on their expression level was measured (Supplementary Fig. S20D). This evidence concerns the gene SERPINE1 and colorectal carcinoma.