Western Blot assays showed that when ovarian cancer cells were treated with cisplatin or niraparib, respectively, high expression of LOC730101 inhibited the BECN1-VPS34 complexes compared to controls and promotes the formation of BECN1-Bcl2 complex and thus inhibited the formation of BECN1-VPS34 autophagosomes, while knockdown of LOC730101 promoted the specific dissociation of BECN1-Bcl2 complex and thus the formation of BECN1-VPS34 autophagosomes compared with the control group (Fig. 4J). This evidence concerns the gene PIK3C3 and ovarian carcinoma.