The highest quartiles of Eotaxin, IL8, OPN, PARC, Fas, MCP1, MPO, STC1, TNFα, and VEGFA were each associated with significantly increased risk for four health outcomes; the highest quartiles of TNFR1, Activin A, and μPAR were each associated with significantly increased risk for five health outcomes, and the highest quartile of GDF15, IL6, MMP1, MMP7, and TNFR2 were associated with significantly increased risk for all six major health outcomes, besides cancer. This evidence concerns the gene GDF15 and cancer.