SLC39A8 and schizophrenia: SLC39A8 encodes a metal ion transporter that modulates neurotransmitter receptor glycosylation (62), and this locus has also shown genome-wide significant associations with schizophrenia (47), intelligence (63) educational attainment (48), and quantitative magnetic susceptibility—an MRI-based measure that is sensitive to iron deposition, myelin, and calcification—in the caudate, substantia nigra, and pallidum (64).