For example, for voxel-wise volumetric analysis, the locus intronic to PPP2R3A [index single-nucleotide polymorphism (SNP) rs13082684, which was the most significant dyslexia-disposing variant in the 23andME GWAS] was associated with lower volume in the right posterior insula and Heschl’s gyrus, and deep subcortical structures spanning the internal capsule, anterior thalamus, and anterior thalamic radiations (Fig. 3). Here, PPP2R3A is linked to dyslexia.