AKT1 and thromboangiitis obliterans: Direct comparison of our results with those obtained by Mulvihill et al. [8] is difficult owing to differences in cell type (mouse 3T3 overexpressing human IGF-1R in the study by Mulvihill et al. vs human OFs of TAO patients in our study) and experimental conditions (phosphorylation level of Akt, 15 min after IGF-1 treatment in Mulvihill et al.’s study vs 5 min after IGF-1 treatment in ours).