In addition to exhibiting a Trp53 mutation and the absence of Fgfr3 and Ras mutations (Figure 2E), the female BALB/c UTUC mouse model mimicked the C3 gene expression subtype of the TP53/MDM2 mutation or triple‐negative mutation subtypes of human UTUC.8 This evidence concerns the gene MDM2 and renal pelvis/ureter urothelial carcinoma.