We found that 78.7% (37/47) of the genes (Supplementary Table S10) aligned with those in the TCGA cohort (Figure 2E)17 and 77.8% (14/18; Supplementary Table S11) of the gene mutations in this model aligned with those in the OU cohort (Supplementary Figure S3C)17; Fgfr3 or Ras mutations were absent, as in a previously reported BC model.27, 29. The gene discussed is FGFR3; the disease is breast cancer.