In this study, proinflammatory cytokines including IL‐1β, IL‐2, IL‐5, IL‐6, IL‐8, IL‐12p70, IL‐17, and TNF alpha were all significantly higher in COVID‐19 patients in the bacteria‐positive group than in the bacteria‐negative group, while there were no significant differences in IL‐4 and IL‐10 levels. The gene discussed is TNF; the disease is COVID-19.