analyzed the functional enrichment of differentially expressed genes on the basis of Gene Expression Omnibus microarray datasets, and the results revealed that the expression of the IRE1α pathway is significantly upregulated in intracranial aneurysms and that the IRE1α pathway is highly related to FKBP14, Bax, and SEC61B expression.124. This evidence concerns the gene ERN1 and Dilatation of the cerebral artery.