Importantly, the comparison of CD4+ T cells in CCI versus rapid recovery sepsis survivors revealed 9 differentially upregulated genes in CCI that are associated with cell activation and proliferation (CD4, CD27, CEBPB, DHPS, SLAMF1, LAPTM5, FADD, RASAL3, and TMIGD2) (71). This evidence concerns the gene RASAL3 and Sepsis.