A recent investigation (6) proposes a study plan for patients with LTP allergy with the determination of levels of IgE specific to Pru p 3, Jug r 3, Ara h 9 and Cor a 8. It has been shown sensitization to Pru p 3, Ara h 9 or Cor a 8 was prevalent among people with food allergy and systemic reactions had higher values of Pru p 3, Ara h 9 and Cor a 8 than patients with oral allergy syndrome (OAS) (7). The gene discussed is IGHE; the disease is microphthalmia with limb anomalies.