Researchers proposed that, in addition to its function at the neuromuscular junction, AGRN might also participate in the onset and progression of diverse tumors, including oral squamous cell carcinoma, hepatocellular carcinoma, and cholangiocarcinoma (Kawahara et al., 2014; Rivera et al., 2018; He et al., 2021; Somorácz et al., 2010; Yan et al., 2018). The gene discussed is AGRN; the disease is cholangiocarcinoma.