In order the understand the involvement of m6A in neurodegenerative disorders, a study focused on a double transgenic mouse model (APPNL‐G‐F/MAPTP301S) that exhibits major AD pathologies, including beta‐amyloid peptides (Aβ) plaque accumulation, tau pathology, inflammation, and neurodegeneration. The gene discussed is MAPT; the disease is Alzheimer disease.