Targeting hepatocellular carcinoma (HCC), Fang et al. designed a hybrid micelle system modified by the peptide Ala-Pro-Asp-Thr-Lys-Thr-Gln (APDTKTQ), aimed at the receptor for advanced glycation end products (RAGE), which is overexpressed in HCC. Here, AGER is linked to hepatocellular carcinoma.