AKT1 and cancer: Role of specific pathways, such as mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) along with its negative regulator phosphatase and TENsin homolog (PTEN), Hedgehog (Hh), and the Hippo pathways involved in cancer cell proliferation and survival have been elucidated by numerous researchers [7–11].