The furin cleavage site (FCS) at the S1/S2 domain junction of the SARS-CoV-2 spike (S) glycoprotein has been recurrently discussed in the context of SARS-CoV-2 origins, SARS-CoV-2 virulence, and COVID-19 pathogenicity [1, 2]. Here, FURIN is linked to COVID-19.