CASC2 and systemic lupus erythematosus: Besides, we shed light on the direct relation between lncRNA CASC2 and miR-155 (act as a sponge) in the pathogenesis of SLE and represent them as non-invasive biomarkers that are used in the diagnosis and detection of disease severity of SLE, as well as their role in discriminating between LN and non-LN patients.