MAPT and Alzheimer disease: Seeding‐based mouse models, in which pathological tau from post‐mortem human brains is injected into non‐transgenic mice, have shown promise in more accurately replicating the patterns of tau pathology observed in human diseases such as AD, CBD, and PSP.[106, 107] Additionally, more sophisticated in vitro models, such as organoids and induced neurons (iNeurons),[108, 109] are being developed.