FMR1 and fragile X syndrome: An update of these guidelines also includes screening forhemoglobinopathies for all candidates, as well as testing for the CGG expansion ofthe Fragile X Messenger Ribonucleoprotein 1 (FMR1) gene,responsible for the Fragile X syndrome, even in the absence of family history (Mertes et al., 2018; Practice Committee of the American Society forReproductive Medicine and the Practice Committee for the Society for AssistedReproductive Technology, 2021).