For example, genes encoding for APOE and APOJ lipoproteins, neuronal ABCA transporters and receptor‐mediated endocytic proteins like LRP1, phosphatidylinositol binding clathrin assembly protein (PICALM), CD2‐associated protein (CD2AP), among others, have been identified as AD risk factors (Victor et al. 2022; Moulton et al. 2021) (Table 2). Here, PICALM is linked to Alzheimer disease.