Non-small cell lung cancer exhibits potential positive causal relationships with Cystatin C (β: 0.022, P: 0.006, FDR: 0.054), and C-reactive protein (β: 0.013, P: 0.04, FDR: 0.28), a clear negative causal relationship with albumin (β: -0.024, P: 0.002, FDR: 0.016*), and potential negative causal relationships with phosphate (β: -0.013, P: 0.008, FDR: 0.072), and urine potassium (β: -0.011, P: 0.012, FDR: 0.108). This evidence concerns the gene CST3 and non-small cell lung carcinoma.