The renal EAS is easily misdiagnosed as epithelioid hemangioendothelioma (EHE), as it could show similar characteristics in immunohistochemical staining, such as being positive for CD31, CD34, and ERG, but the results of Ki-67, WWTR1-CAMTA1, and YAP1-TFE3 might be helpful in differential diagnosis (21, 22). This evidence concerns the gene CD34 and epithelioid hemangioendothelioma.