On the other hand, the AML extracts showed inhibition in TNF-α significantly by 1,000 μg/ml of ethanolic and acetone extracts (p<0.001) for colon cancer (Figure 7B), p<0.01 for acetone and hexane, and p<0.05 for aqueous extract. The gene discussed is TNF; the disease is malignant colon neoplasm.