Further research results show that the protein expressions of NLRP3, Caspase-1p20, and GSDMD-N in the brain tissue of model group rats were significantly increased, while the protein expressions of NLRP3, Caspase-1p20, and GSDMD-N in the brain tissue of TAC group rats were significantly decreased. This evidence concerns the gene NLRP3 and persistent truncus arteriosus.