MIG and its receptor CXCR3 have been reported as being important in the development of autoimmune thyroiditis (10) and experimental evidence also supports the concept that MIG and IP-10 and their receptor, CXCR3, play an important role in the initial stage of autoimmune disorders involving endocrine glands (14) supporting our finding of association between MIG and thyroiditis and hypophysitis. The gene discussed is CXCL10; the disease is autoimmune thyroid disease.