VEGFA and myocardial infarction: Also, in I/R-induced pig models of myocardial infarction, exosomal miR-181b-5p from M2 macrophages suppresses the number of CCR2+ macrophages in favor of the polarization of macrophages toward the M2 phenotype, which facilitates the migration and pro‐angiogenic vascular endothelial growth factor (VEGF) expression by endothelial cells, leading to improved angiogenesis and cardioprotective effect (71).