NES and neoplasm: Nestin positivity and high expression level showed significant associations with aggressive tumor parameters such as high grade (P=0.011 and 0.008), wider tumor extension (P=0.001 and 0.011), advanced stage (P=0.017 and 0.001), higher MVD (P=0.05 and 0.026) and metastasis (P=0.045 and 0.013).