NFKB1 and heart failure: Pu et al. found in rat myocardial infarction models that the endothelial receptor 1 (LOX1) of oxidized low-density lipoprotein (LDL) enhances cell damage by activating the NF-κB p65/Caspase-9 pathway, while mesenchymal stem cell-derived exosomes improve heart failure in rats by inhibiting miR-30e targeting LOX1 (42).