Fibroblast growth factor 21 (FGF21), a member of the endocrine subfamily, is produced in the liver and is a 210-amino acid polypeptide that plays a crucial role in atherosclerosis, blood sugar regulation, and lipid metabolism (Jin, Xia & Han, 2021; Szczepańska & Gietka-Czernel, 2022). Here, FGF21 is linked to atherosclerosis.