In this study, we established a dexamethasone‐induced muscle atrophy model using C2C12 myoblasts, which exhibited a significantly lower myotube area, fusion index and myotube diameter compared to those of control cells (Figure 1a–d; control (CTL) vs. dexamethasone‐induced muscle atrophy model (DEX) when stained with MYH (green) and DAPI (blue). This evidence concerns the gene MUTYH and Atrophy.