A recent work revealed that YAP is selectively activated by bile acids in lymph node‐metastatic tumors, and functions as a crucial driver for tumor lymph node metastasis through selective stimulation of fatty acid oxidation (FAO).[39] As PA is implicated in regulating the Hippo/YAP pathway,[41] whether and how the Hippo/YAP pathway plays a role in PA‐promoted metastasis remains unknown. This evidence concerns the gene YAP1 and neoplasm.