Mounting evidence indicates that PA affects cancer metastasis through distinct mechanisms in different contexts.[39, 76] Previous studies as well as our current in vivo investigation indicate that the Hippo/YAP pathway is implicated in cancer metastasis.[39, 40, 77] A variety of studies documented that PA affected the Hippo/YAP signaling in diverse contexts, however, whether and how YAP plays a role in PA‐promoted metastasis remains unknown. Here, YAP1 is linked to cancer.