Multiplex IHC revealed that Granzyme‐K+PD‐1+CD8+ T cells were primarily accumulated in TLSs (Figure 5H), and the density of Granzyme‐K+PD‐1+CD8+ T cells in the tumor regions was significantly increased in the post‐HAIC samples (Figure 5H–J). This evidence concerns the gene PDCD1 and neoplasm.