RRM2 and nasopharyngeal carcinoma: It has been found that miR-409-3P can inhibit nasopharyngeal carcinoma development by negatively regulating the expression of RRM2,[33] and can also regulate FABP4 in ovarian cancer cells and thus affect the metabolic pathways in ovarian cancer cells,[34] and the analysis in AIS may be that miR-409-3P can target peroxisome proliferator-activated receptor γ to regulate the activation of microcellularity and inflammatory factor expression.